ISSN: 1223-1533

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Authors: Shi-feng Li, Ji-hong Shen, Wei Wang, Young-Sheng Wang, Zhong-Jian Li


Backgroud: Obstructive sleep apnea syndrome(OSAS) is a potentially serious sleep disorder in which breathing repeatedly stops and starts during sleep. It occurs when your throat muscles intermittently relax and block your airway during sleep. Polysomnography is the accepted methodology for the diagnosis. A reliable non-invasive method (as a regular 24-hour AECG system with a specific software) would be valuable for the screening of OSAS patients. We conducted this study to explore the diagnostic value of 24-hour AECG in obstructive sleep apnea syndrome.


Method: The overnight sleep investigation was administered in 102 subjects by 24 hour AECG monitoring, at the same time polysomnogram was carried out on the same patient. They both worked out each conclusion without consultation each other. 13 items in 24-hour AECG were set for the screening, that is [D/N] SDNN, [D/N] SDNN index, [D/N]r-MSSD, [(D+N)/N]total power, [(D+N)/N] VLF power,% VLF to total power, [D/N] LF power, [D/N] LF to HF ratio, Ventricular Arrhythmias, [D/N]QTc, Sleep QTc Variation, Average HR, Sleep HR Variations Minute 15bpm.


Results: When sleep asphyxia risk analysis grade >5,the sensitivity of Holter diagnosing OSAS was 70.1%,the specificity42.6%,and the diagnoses according rate 56.8%.Whereas,when sleep asphyxia risk analysis grade >5 and the actual value was two times more than the normal value, the specificity83.6%,and the diagnoses according rate 88.4%,but the sensitivity came lower.

Frequence- domain HRV analysis methods were more sensitive than time-domain HRV analysis method.


Conclusions: 24-hour AECG is a simple and easy tool as a non-invasive means of assessing and filtrating OSAS. There are good consistencies between 24-hour AECG and polysomnography. 24-hour AECG is worth popularizing application in clinic.