IS IT POSSIBLE TO TREAT VENTRICULAR ARRHYTHMIA WITHOUT ANTIARRHYTHMIC DRUGS?
The aim of the study is to define the possibility of treatment idiopathic ventricular arrhythmia (VA) with anxiolytic in patients with anxiety.
Methods: Inclusion criteria were an abnormal amount of idiopathic VA during the Holter ECG, the medium or high anxiety level according to psychological questionnaires. All patients underwent a clinical examination, ECG, echocardiogram, ETT, psychological questionnaires, psychological counseling, emotional Stroop Color and Word Test (SCWT).
There were two groups out of 56 patients. Group I included 20 patients (12 women), mean age 46.6±14,7 years, with ventricular ectopic complexes (VEC) in an amount 11354,7 ± 536,3 / day, which received anxiolytic in a therapeutic dose for 30 days. Control group consisted of 20 patients (11 women), 45,2±11,3 years, VEC 12467,2 ± 423,1 /day, without any therapy. Holter ECG, SCWT and psychological questionnaires were re-conducted in 30 days.
Results: The average number of VEC decreased significantly from 478,8 ± 47,2 to 155,7 ± 73,2 (temp = 2.4, p : 0,05) in the first group according to Holter ECG, while in the control group - from 512,5 ± 67,5 to 467,3 ± 39,4 (temp = 0.5, p 0,05). Positive SCWT became negative in 95% of patients in the first group, i.e. arrhythmia was not provocated (cemp = 3.1, p : 0,01). The number of patients with middle and high anxiety level has decreased more than 3 times (cemp = 1.85, p:0,05), after therapy with anxiolytic. There were no significant changes in the second group in the results of questionnaires and SCWT.
Conclusions: This study shows that psychogenic factors play an important, and sometimes - a decisive role in the genesis of idiopathic VA. Anxiolytic can be recommended to patients with VA and high anxiety level.