REPOLARIZATION PHASE ABNORMALITIES IN YOUNG WOMEN - DIAGNOSTIC PITFALLS AND DIFFICULTIES
Electrocardiogram, particularly its repolarization phase, may change especially in young women, which creates difficulties in interpretation and differential diagnosis between normal variants and pathological aspects.
Our aim was to research these particularities in young patients and their subsequent classification after complex clinical and paraclinical evaluation and also gender related particularities.
Method. We selected from the cases hospitalized in 2012 a number of 90 patients (p) aged under 50 years, 50 men and
40 women with ST depression. Clinical data, ECG, chest radiography, echocardiography, stress test, coronary angioCT or pulmonary angioCT were recorded.
Results. Males were most commonly diagnosed with: 28p with coronary heart disease, 5p with acute miopericarditis,
6 with pulmonary thromboembolism, 3 with early repolarization, 3p with drug usage and 5p without cardiac disease. There were 22 women with suggestive clinical signs and positive stress test without coronary artery disease, 11 with coronary artery disease, 6 with pulmonary thromboembolism, 6p had miopericarditis, 3 Tako-tsubo, 1 aortic dissection and 1p with abnormal origin of the coronary arteries.
Conclusions. Women have frequently electrocardiogram abnormalities unrelated to coronary pathology, but rarely repolarization phase anomalies and nonspecific subjective symptoms can be diagnostic elements of life-threatening diseases.